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Aspirin and caffeine

Generic name: aspirin and caffeine [  AS-pir-in-and-KAF-een ]
Brand names: Alka-Seltzer Hangover Relief, Alka-Seltzer Morning Relief, Anacin, Anacin Extra Strength, Bayer Back and Body, ... show all 14 brands
Dosage forms: oral powder for reconstitution (1000 mg-65 mg; 845 mg-65 mg), oral tablet (400 mg-32 mg; 421 mg-32 mg; 500 mg-32 mg; 500 mg-32.5 mg), ... show all 3 dosage forms
Drug class: Analgesic combinations

Medically reviewed by Drugs.com on Mar 22, 2024. Written by Cerner Multum.

What is aspirin and caffeine?

Aspirin and caffeine is a combination product used to relieve minor aches and pains such as headaches, muscle pain, minor arthritis pain, menstrual cramps, and fever or body aches caused by the common cold in adults and children at least 12 years old. Aspirin and caffeine is sometimes used in adults to relieve conditions associated with hangover.

Aspirin and caffeine may also be used for purposes not listed in this medication guide.

Aspirin and caffeine side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Limit the use of caffeine-containing medications, coffee, tea, cola, energy drinks or other sources of caffeine while taking this product. Using too much caffeine may cause nervousness, irritability, sleeplessness, and, rapid heart beat.

Aspirin and caffeine may cause serious side effects. Stop using aspirin and caffeine and call your doctor at once if you have:

Common side effects of aspirin and caffeine may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Aspirin may cause stomach or intestinal bleeding, which can be fatal.

Aspirin can also cause a severe allergic reaction. Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Limit the use of caffeine-containing medications, coffee, tea, cola, energy drinks or other sources of caffeine while taking this product. Using too much caffeine may cause nervousness, irritability, sleeplessness, and, rapid heart beat.

Using aspirin and caffeine in a child or teenager with flu symptoms or chickenpox can cause a serious or fatal condition called Reye's syndrome.

Before taking this medicine

You should not use this medicine if you are allergic to aspirin or caffeine, or if you have:

Do not give this medication to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin and caffeine can cause Reye's syndrome, a serious and sometimes fatal condition in children.

This medicine may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are taking aspirin and caffeine, especially:

Ask a doctor or pharmacist if this medicine is safe to use if you have or have ever had:

This medicine may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

Stop using this medicine and tell your doctor right away if you become pregnant. Aspirin and caffeine can cause injury or death to the unborn baby if you use the medicine during your third trimester.

Ask a doctor before using this medicine if you are breastfeeding.

How should I take aspirin and caffeine?

Use exactly as directed on the label, or as prescribed by your doctor.

Aspirin and caffeine is usually taken every 6 hours with a full glass of water.

Taking more than your recommended dose will not make aspirin and caffeine more effective, and may cause serious side effects.

Take with food if aspirin and caffeine upsets your stomach.

If you need surgery, tell the surgeon ahead of time that you are using aspirin and caffeine. You may need to stop using the medicine for a short time.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Aspirin and caffeine is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking aspirin and caffeine?

Drinking alcohol may increase your risk of stomach bleeding.

What other drugs will affect aspirin and caffeine?

Ask a doctor or pharmacist before using aspirin and caffeine with any other medicines, especially:

This list is not complete. Other drugs may affect aspirin and caffeine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.